1K01CA124461/CA/NCI NIH HHS/United States[Grants and Funding] - Search Results

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Subject: 1K01CA124461/CA/NCI NIH HHS/United States[Grants - PubMed

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Telomere dysfunction and tumour suppression: the senescence connection.

Deng Y, Chan SS, Chang S. Deng Y, et al. Nat Rev Cancer. 2008 Jun;8(6):450-8. doi: 10.1038/nrc2393. Nat Rev Cancer. 2008. PMID: 18500246 Free PMC article. Review.

Dysfunctional telomeres activate an ATM-ATR-dependent DNA damage response to suppress tumorigenesis.

Guo X, Deng Y, Lin Y, Cosme-Blanco W, Chan S, He H, Yuan G, Brown EJ, Chang S. Guo X, et al. EMBO J. 2007 Nov 14;26(22):4709-19. doi: 10.1038/sj.emboj.7601893. Epub 2007 Oct 18. EMBO J. 2007. PMID: 17948054 Free PMC article.

Pot1b deletion and telomerase haploinsufficiency in mice initiate an ATR-dependent DNA damage response and elicit phenotypes resembling dyskeratosis congenita.

He H, Wang Y, Guo X, Ramchandani S, Ma J, Shen MF, Garcia DA, Deng Y, Multani AS, You MJ, Chang S. He H, et al. Mol Cell Biol. 2009 Jan;29(1):229-40. doi: 10.1128/MCB.01400-08. Epub 2008 Oct 20. Mol Cell Biol. 2009. PMID: 18936156 Free PMC article.

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