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Decreased nutrient-stimulated insulin secretion in chronically hypoglycemic late-gestation fetal sheep is due to an intrinsic islet defect.

Rozance PJ, Limesand SW, Hay WW Jr. Rozance PJ, et al. Am J Physiol Endocrinol Metab. 2006 Aug;291(2):E404-11. doi: 10.1152/ajpendo.00643.2005. Epub 2006 Mar 28. Am J Physiol Endocrinol Metab. 2006. PMID: 16569758 Free article.

Prolonged maternal amino acid infusion in late-gestation pregnant sheep increases fetal amino acid oxidation.

Rozance PJ, Crispo MM, Barry JS, O'Meara MC, Frost MS, Hansen KC, Hay WW Jr, Brown LD. Rozance PJ, et al. Am J Physiol Endocrinol Metab. 2009 Sep;297(3):E638-46. doi: 10.1152/ajpendo.00192.2009. Epub 2009 Jul 14. Am J Physiol Endocrinol Metab. 2009. PMID: 19602583 Free PMC article.

Chronic fetal hypoglycemia inhibits the later steps of stimulus-secretion coupling in pancreatic beta-cells.

Rozance PJ, Limesand SW, Zerbe GO, Hay WW Jr. Rozance PJ, et al. Am J Physiol Endocrinol Metab. 2007 May;292(5):E1256-64. doi: 10.1152/ajpendo.00265.2006. Epub 2007 Jan 9. Am J Physiol Endocrinol Metab. 2007. PMID: 17213478 Free article.

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