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Quorum sensing N-Acyl homoserine lactones are a new class of anti-schistosomal.
Whiteland H, Crusco A, Bloemberg LW, Tibble-Howlings J, Forde-Thomas J, Coghlan A, Murphy PJ, Hoffmann KF. Whiteland H, et al. PLoS Negl Trop Dis. 2020 Oct 19;14(10):e0008630. doi: 10.1371/journal.pntd.0008630. eCollection 2020 Oct. PLoS Negl Trop Dis. 2020. PMID: 33075069 Free PMC article.
Structural Requirements for Dihydrobenzoxazepinone Anthelmintics: Actions against Medically Important and Model Parasites: Trichuris muris, Brugia malayi, Heligmosomoides polygyrus, and Schistosoma mansoni.
Partridge FA, Bataille CJR, Forman R, Marriott AE, Forde-Thomas J, Häberli C, Dinsdale RL, O'Sullivan JDB, Willis NJ, Wynne GM, Whiteland H, Archer J, Steven A, Keiser J, Turner JD, Hoffmann KF, Taylor MJ, Else KJ, Russell AJ, Sattelle DB. Partridge FA, et al. ACS Infect Dis. 2021 May 14;7(5):1260-1274. doi: 10.1021/acsinfecdis.1c00025. Epub 2021 Apr 2. ACS Infect Dis. 2021. PMID: 33797218 Free PMC article.