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Synthetic Retinoid Sulfarotene Selectively Inhibits Tumor-Repopulating Cells of Intrahepatic Cholangiocarcinoma via Disrupting Cytoskeleton by P-Selectin/PSGL1 N-Glycosylation Blockage.
Adv Sci (Weinh). 2024 Nov 28:e2407519. doi: 10.1002/advs.202407519. Online ahead of print.
Adv Sci (Weinh). 2024.
PMID: 39605300
ZSH-2208: A novel retinoid with potent anti-tumour effects on ESCC stem cells via RARγ-TNFAIP3 axis.
Chen R, Huang X, Hou J, Ni J, Zhao W, Li Q, Jiao H, Cao X.
Chen R, et al.
Clin Transl Med. 2025 Jan;15(1):e70148. doi: 10.1002/ctm2.70148.
Clin Transl Med. 2025.
PMID: 39724264
Free PMC article.
Mechanistic exploration revealed that ZSH-2208 inhibits the growth of ESCC-TRCs through modulation of the RARgamma-TNFAIP3 axis. The clinical significance of the key molecule TNFAIP3 in ESCC has also been demonstrated. RESULTS: This study introduces ZSH-2208, a novel retin …
Mechanistic exploration revealed that ZSH-2208 inhibits the growth of ESCC-TRCs through modulation of the RARgamma-TNFAIP3 axis. The clinica …
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