2023YFE0206500/National Key Research and Development Program[Grants and Funding] - Search Results

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Structure-based design of diarylpyrimidines and triarylpyrimidines as potent HIV-1 NNRTIs with improved metabolic stability and drug resistance profiles.

Xie M, Wang Z, Zhao F, Li Y, Zhuo Z, Li X, De Clercq E, Pannecouque C, Zhan P, Liu X, Kang D. Xie M, et al. J Med Virol. 2024 Mar;96(3):e29502. doi: 10.1002/jmv.29502. J Med Virol. 2024. PMID: 38450817

Discovery of Novel Amino Acids (Analogues)-Substituted Thiophene[3,2-d]pyrimidine Derivatives as Potent HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors: Design, Synthesis, and Biological Evaluation.

Zhuo Z, Wang Z, Jing L, Zhang T, Ge A, Zhou Z, Liu Y, Li X, De Clercq E, Pannecouque C, Zhan P, Liu X, Kang D. Zhuo Z, et al. Int J Mol Sci. 2024 Aug 20;25(16):9028. doi: 10.3390/ijms25169028. Int J Mol Sci. 2024. PMID: 39201714 Free PMC article.

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