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Page 1
Single-cell analysis defines a pancreatic fibroblast lineage that supports anti-tumor immunity.
Hutton C, Heider F, Blanco-Gomez A, Banyard A, Kononov A, Zhang X, Karim S, Paulus-Hock V, Watt D, Steele N, Kemp S, Hogg EKJ, Kelly J, Jackstadt RF, Lopes F, Menotti M, Chisholm L, Lamarca A, Valle J, Sansom OJ, Springer C, Malliri A, Marais R, Pasca di Magliano M, Zelenay S, Morton JP, Jørgensen C. Hutton C, et al. Cancer Cell. 2021 Sep 13;39(9):1227-1244.e20. doi: 10.1016/j.ccell.2021.06.017. Epub 2021 Jul 22. Cancer Cell. 2021. PMID: 34297917 Free PMC article.
Compartmentalisation of RAC1 signalling.
Payapilly A, Malliri A. Payapilly A, et al. Curr Opin Cell Biol. 2018 Oct;54:50-56. doi: 10.1016/j.ceb.2018.04.009. Epub 2018 Apr 30. Curr Opin Cell Biol. 2018. PMID: 29723737 Review.
A TIAM1-TRIM28 complex mediates epigenetic silencing of protocadherins to promote migration of lung cancer cells.
Ginn L, Maltas J, Baker MJ, Chaturvedi A, Wilson L, Guilbert R, Amaral FMR, Priest L, Mole H, Blackhall F, Diamantopoulou Z, Somervaille TCP, Hurlstone A, Malliri A. Ginn L, et al. Proc Natl Acad Sci U S A. 2023 Oct 3;120(40):e2300489120. doi: 10.1073/pnas.2300489120. Epub 2023 Sep 25. Proc Natl Acad Sci U S A. 2023. PMID: 37748077 Free PMC article.
The Rac-GEF Tiam1 controls integrin-dependent neutrophil responses.
Hornigold K, Baker MJ, Machin PA, Chetwynd SA, Johnsson AK, Pantarelli C, Islam P, Stammers M, Crossland L, Oxley D, Okkenhaug H, Walker S, Walker R, Segonds-Pichon A, Fukui Y, Malliri A, Welch HCE. Hornigold K, et al. Front Immunol. 2023 Nov 21;14:1223653. doi: 10.3389/fimmu.2023.1223653. eCollection 2023. Front Immunol. 2023. PMID: 38077328 Free PMC article.
POTEE promotes breast cancer cell malignancy by inducing invadopodia formation through the activation of SUMOylated Rac1.
Martínez-López A, García-Casas A, Infante G, González-Fernández M, Salvador N, Lorente M, Mendiburu-Eliçabe M, Gonzalez-Moreno S, Villarejo-Campos P, Velasco G, Malliri A, Castillo-Lluva S. Martínez-López A, et al. Mol Oncol. 2024 Mar;18(3):620-640. doi: 10.1002/1878-0261.13568. Epub 2023 Dec 27. Mol Oncol. 2024. PMID: 38098337 Free PMC article.
Centrosome separation; a careful balancing act.
Whalley HJ, Malliri A. Whalley HJ, et al. Cell Cycle. 2015;14(19):3001-2. doi: 10.1080/15384101.2015.1080981. Cell Cycle. 2015. PMID: 26313329 Free PMC article. No abstract available.
GEFs: Dual regulation of Rac1 signaling.
Marei H, Malliri A. Marei H, et al. Small GTPases. 2017 Apr 3;8(2):90-99. doi: 10.1080/21541248.2016.1202635. Epub 2016 Jun 17. Small GTPases. 2017. PMID: 27314616 Free PMC article. Review.
25 results