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CSF1R-dependent macrophages in the salivary gland are essential for epithelial regeneration after radiation-induced injury.
McKendrick JG, Jones GR, Elder SS, Watson E, T'Jonck W, Mercer E, Magalhaes MS, Rocchi C, Hegarty LM, Johnson AL, Schneider C, Becher B, Pridans C, Mabbott N, Liu Z, Ginhoux F, Bajenoff M, Gentek R, Bain CC, Emmerson E. McKendrick JG, et al. Sci Immunol. 2023 Nov 3;8(89):eadd4374. doi: 10.1126/sciimmunol.add4374. Epub 2023 Nov 3. Sci Immunol. 2023. PMID: 37922341
Rate of replenishment and microenvironment contribute to the sexually dimorphic phenotype and function of peritoneal macrophages.
Bain CC, Gibson DA, Steers NJ, Boufea K, Louwe PA, Doherty C, González-Huici V, Gentek R, Magalhaes-Pinto M, Shaw T, Bajénoff M, Bénézech C, Walmsley SR, Dockrell DH, Saunders PTK, Batada NN, Jenkins SJ. Bain CC, et al. Sci Immunol. 2020 Jun 19;5(48):eabc4466. doi: 10.1126/sciimmunol.abc4466. Sci Immunol. 2020. PMID: 32561560 Free PMC article.
The transcription factor EGR2 is indispensable for tissue-specific imprinting of alveolar macrophages in health and tissue repair.
McCowan J, Fercoq F, Kirkwood PM, T'Jonck W, Hegarty LM, Mawer CM, Cunningham R, Mirchandani AS, Hoy A, Humphries DC, Jones GR, Hansen CG, Hirani N, Jenkins SJ, Henri S, Malissen B, Walmsley SR, Dockrell DH, Saunders PTK, Carlin LM, Bain CC. McCowan J, et al. Sci Immunol. 2021 Nov 19;6(65):eabj2132. doi: 10.1126/sciimmunol.abj2132. Epub 2021 Nov 19. Sci Immunol. 2021. PMID: 34797692 Free PMC article.