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A prenylated dsRNA sensor protects against severe COVID-19.
Wickenhagen A, Sugrue E, Lytras S, Kuchi S, Noerenberg M, Turnbull ML, Loney C, Herder V, Allan J, Jarmson I, Cameron-Ruiz N, Varjak M, Pinto RM, Lee JY, Iselin L, Palmalux N, Stewart DG, Swingler S, Greenwood EJD, Crozier TWM, Gu Q, Davies EL, Clohisey S, Wang B, Trindade Maranhão Costa F, Freire Santana M, de Lima Ferreira LC, Murphy L, Fawkes A, Meynert A, Grimes G; ISARIC4C Investigators; Da Silva Filho JL, Marti M, Hughes J, Stanton RJ, Wang ECY, Ho A, Davis I, Jarrett RF, Castello A, Robertson DL, Semple MG, Openshaw PJM, Palmarini M, Lehner PJ, Baillie JK, Rihn SJ, Wilson SJ. Wickenhagen A, et al. Science. 2021 Oct 29;374(6567):eabj3624. doi: 10.1126/science.abj3624. Epub 2021 Oct 29. Science. 2021. PMID: 34581622 Free PMC article.
Co-option of epidermal cells enables touch sensing.
Mangione F, Titlow J, Maclachlan C, Gho M, Davis I, Collinson L, Tapon N. Mangione F, et al. Nat Cell Biol. 2023 Apr;25(4):540-549. doi: 10.1038/s41556-023-01110-2. Epub 2023 Mar 23. Nat Cell Biol. 2023. PMID: 36959505 Free PMC article.
Systematic analysis of YFP traps reveals common mRNA/protein discordance in neural tissues.
Titlow JS, Kiourlappou M, Palanca A, Lee JY, Gala DS, Ennis D, Yu JJS, Young FL, Susano Pinto DM, Garforth S, Francis HS, Strivens F, Mulvey H, Dallman-Porter A, Thornton S, Arman D, Millard MJ, Järvelin AI, Thompson MK, Sargent M, Kounatidis I, Parton RM, Taylor S, Davis I. Titlow JS, et al. J Cell Biol. 2023 Jun 5;222(6):e202205129. doi: 10.1083/jcb.202205129. Epub 2023 May 5. J Cell Biol. 2023. PMID: 37145332 Free PMC article.