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Platelet transcription factors license the pro-inflammatory cytokine response of human monocytes.
Hawwari I, Rossnagel L, Rosero N, Maasewerd S, Vasconcelos MB, Jentzsch M, Demczuk A, Teichmann LL, Meffert L, Bertheloot D, Ribeiro LS, Kallabis S, Meissner F, Arditi M, Atici AE, Noval Rivas M, Franklin BS. Hawwari I, et al. EMBO Mol Med. 2024 Aug;16(8):1901-1929. doi: 10.1038/s44321-024-00093-3. Epub 2024 Jul 8. EMBO Mol Med. 2024. PMID: 38977927 Free PMC article.
RNA-binding proteins hnRNPM and ELAVL1 promote type-I interferon induction downstream of the nucleic acid sensors cGAS and RIG-I.
Kirchhoff A, Herzner AM, Urban C, Piras A, Düster R, Mahlberg J, Grünewald A, Schlee-Guimarães TM, Ciupka K, Leka P, Bootz RJ, Wallerath C, Hunkler C, de Regt AK, Kümmerer BM, Christensen MH, Schmidt FI, Lee-Kirsch MA, Günther C, Kato H, Bartok E, Hartmann G, Geyer M, Pichlmair A, Schlee M. Kirchhoff A, et al. EMBO J. 2024 Dec 20. doi: 10.1038/s44318-024-00331-x. Online ahead of print. EMBO J. 2024. PMID: 39707025 Free article.