247301/Canadian Institutes of Health Research/Canada[Grants and Funding] - Search Results

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Requirement and redundancy of the Src family kinases Fyn and Lyn in perforin-dependent killing of Cryptococcus neoformans by NK cells.

Oykhman P, Timm-McCann M, Xiang RF, Islam A, Li SS, Stack D, Huston SM, Ma LL, Mody CH. Oykhman P, et al. Infect Immun. 2013 Oct;81(10):3912-22. doi: 10.1128/IAI.00533-13. Epub 2013 Aug 5. Infect Immun. 2013. PMID: 23918783 Free PMC article.

The NK receptor NKp30 mediates direct fungal recognition and killing and is diminished in NK cells from HIV-infected patients.

Li SS, Kyei SK, Timm-McCann M, Ogbomo H, Jones GJ, Shi M, Xiang RF, Oykhman P, Huston SM, Islam A, Gill MJ, Robbins SM, Mody CH. Li SS, et al. Cell Host Microbe. 2013 Oct 16;14(4):387-97. doi: 10.1016/j.chom.2013.09.007. Cell Host Microbe. 2013. PMID: 24139398 Free article.

An acidic microenvironment increases NK cell killing of Cryptococcus neoformans and Cryptococcus gattii by enhancing perforin degranulation.

Islam A, Li SS, Oykhman P, Timm-McCann M, Huston SM, Stack D, Xiang RF, Kelly MM, Mody CH. Islam A, et al. PLoS Pathog. 2013;9(7):e1003439. doi: 10.1371/journal.ppat.1003439. Epub 2013 Jul 11. PLoS Pathog. 2013. PMID: 23853583 Free PMC article.

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