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Clearance of senescent macrophages ameliorates tumorigenesis in KRAS-driven lung cancer.
Haston S, Gonzalez-Gualda E, Morsli S, Ge J, Reen V, Calderwood A, Moutsopoulos I, Panousopoulos L, Deletic P, Carreno G, Guiho R, Manshaei S, Gonzalez-Meljem JM, Lim HY, Simpson DJ, Birch J, Pallikonda HA, Chandra T, Macias D, Doherty GJ, Rassl DM, Rintoul RC, Signore M, Mohorianu I, Akbar AN, Gil J, Muñoz-Espín D, Martinez-Barbera JP. Haston S, et al. Cancer Cell. 2023 Jul 10;41(7):1242-1260.e6. doi: 10.1016/j.ccell.2023.05.004. Epub 2023 Jun 1. Cancer Cell. 2023. PMID: 37267953 Free article.
Cellular senescence in cancer: from mechanisms to detection.
Ou HL, Hoffmann R, González-López C, Doherty GJ, Korkola JE, Muñoz-Espín D. Ou HL, et al. Mol Oncol. 2021 Oct;15(10):2634-2671. doi: 10.1002/1878-0261.12807. Epub 2020 Oct 22. Mol Oncol. 2021. PMID: 32981205 Free PMC article. Review.
Galacto-conjugation of Navitoclax as an efficient strategy to increase senolytic specificity and reduce platelet toxicity.
González-Gualda E, Pàez-Ribes M, Lozano-Torres B, Macias D, Wilson JR 3rd, González-López C, Ou HL, Mirón-Barroso S, Zhang Z, Lérida-Viso A, Blandez JF, Bernardos A, Sancenón F, Rovira M, Fruk L, Martins CP, Serrano M, Doherty GJ, Martínez-Máñez R, Muñoz-Espín D. González-Gualda E, et al. Aging Cell. 2020 Apr;19(4):e13142. doi: 10.1111/acel.13142. Epub 2020 Mar 31. Aging Cell. 2020. PMID: 32233024 Free PMC article.
Targeting senescent cells in translational medicine.
Paez-Ribes M, González-Gualda E, Doherty GJ, Muñoz-Espín D. Paez-Ribes M, et al. EMBO Mol Med. 2019 Dec;11(12):e10234. doi: 10.15252/emmm.201810234. Epub 2019 Nov 19. EMBO Mol Med. 2019. PMID: 31746100 Free PMC article. Review.
17 results