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Inactivation of gadd45a sensitizes epithelial cancer cells to ionizing radiation in vivo resulting in prolonged survival.
Cancer Res. 2008 May 15;68(10):3579-83. doi: 10.1158/0008-5472.CAN-07-5533.
Cancer Res. 2008.
PMID: 18483238
Free PMC article.
Apoptosis is the essential target of selective pressure against p53, whereas loss of additional p53 functions facilitates carcinoma progression.
Lu X, Yang C, Yin C, Van Dyke T, Simin K.
Lu X, et al.
Mol Cancer Res. 2011 Apr;9(4):430-9. doi: 10.1158/1541-7786.MCR-10-0277. Epub 2011 Mar 8.
Mol Cancer Res. 2011.
PMID: 21385880
Free PMC article.
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