Assessment of liver fibrosis by transient elastography in patients with HIV and hepatitis B virus coinfection in Nigeria

Clin Infect Dis. 2013 Dec;57(12):e189-92. doi: 10.1093/cid/cit564. Epub 2013 Sep 6.

Abstract

We describe the prevalence and risk factors for advanced liver fibrosis (≥9.3 kPa) using transient elastography in human immunodeficiency virus (HIV)–monoinfected and HIV/HBV (hepatitis B virus)–coinfected, antiretroviral naive adults in Nigeria. HBV coinfection and HBV DNA levels significantly increased the risk of advanced fibrosis in HIV and HIV/HBV patients, respectively.

Keywords: Africa; HBV; HIV; liver fibrosis.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Cross-Sectional Studies
  • Elasticity Imaging Techniques
  • Female
  • HIV Infections / epidemiology
  • HIV Infections / pathology*
  • Hepatitis B / epidemiology
  • Hepatitis B / pathology*
  • Humans
  • Liver Cirrhosis / diagnostic imaging
  • Liver Cirrhosis / epidemiology
  • Liver Cirrhosis / physiopathology
  • Liver Cirrhosis / virology*
  • Male
  • Multivariate Analysis
  • Nigeria / epidemiology
  • Risk Factors