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Combination of p38 MAPK inhibitor with PD-L1 antibody effectively prolongs survivals of temozolomide-resistant glioma-bearing mice via reduction of infiltrating glioma-associated macrophages and PD-L1 expression on resident glioma-associated microglia.
Dang W, Xiao J, Ma Q, Miao J, Cao M, Chen L, Shi Y, Yao X, Yu S, Liu X, Cui Y, Zhang X, Bian X. Dang W, et al. Brain Tumor Pathol. 2021 Jul;38(3):189-200. doi: 10.1007/s10014-021-00404-3. Epub 2021 Jul 6. Brain Tumor Pathol. 2021. PMID: 34231121