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Activation of interferon response through toll-like receptor 3 impacts viral pathogenesis and pulmonary toll-like receptor expression during respiratory syncytial virus and influenza infections in the cotton rat Sigmodon hispidus model.
Boukhvalova MS, Sotomayor TB, Point RC, Pletneva LM, Prince GA, Blanco JC. Boukhvalova MS, et al. J Interferon Cytokine Res. 2010 Apr;30(4):229-42. doi: 10.1089/jir.2009.0025. J Interferon Cytokine Res. 2010. PMID: 20038196 Free PMC article.
Respiratory syncytial virus fusion protein-induced toll-like receptor 4 (TLR4) signaling is inhibited by the TLR4 antagonists Rhodobacter sphaeroides lipopolysaccharide and eritoran (E5564) and requires direct interaction with MD-2.
Rallabhandi P, Phillips RL, Boukhvalova MS, Pletneva LM, Shirey KA, Gioannini TL, Weiss JP, Chow JC, Hawkins LD, Vogel SN, Blanco JC. Rallabhandi P, et al. mBio. 2012 Aug 7;3(4):e00218-12. doi: 10.1128/mBio.00218-12. Print 2012. mBio. 2012. PMID: 22872782 Free PMC article.