AI087671/AI/NIAID NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2010	1
2011	3
2012	2
2013	3
2014	6
2015	3
2016	5
2017	1
2018	4
2019	3
2020	1
2023	1
2025	0

1

Delgado JL, Hsieh CM, Chan NL, Hiasa H. Delgado JL, et al. Biochem J. 2018 Jan 23;475(2):373-398. doi: 10.1042/BCJ20160583. Biochem J. 2018. PMID: 29363591 Free PMC article. Review.

2

Mechanism of quinolone action and resistance.

Aldred KJ, Kerns RJ, Osheroff N. Aldred KJ, et al. Biochemistry. 2014 Mar 18;53(10):1565-74. doi: 10.1021/bi5000564. Epub 2014 Mar 7. Biochemistry. 2014. PMID: 24576155 Free PMC article. Review.

3

DNA Topoisomerases as Targets for Antibacterial Agents.

Hiasa H. Hiasa H. Methods Mol Biol. 2018;1703:47-62. doi: 10.1007/978-1-4939-7459-7_3. Methods Mol Biol. 2018. PMID: 29177732

4

Role of the Water-Metal Ion Bridge in Quinolone Interactions with Escherichia coli Gyrase.

Carter HE, Wildman B, Schwanz HA, Kerns RJ, Aldred KJ. Carter HE, et al. Int J Mol Sci. 2023 Feb 2;24(3):2879. doi: 10.3390/ijms24032879. Int J Mol Sci. 2023. PMID: 36769202 Free PMC article.

5

The C7-aminomethylpyrrolidine group rescues the activity of a thio-fluoroquinolone.

Lentz SRC, Chheda PR, Oppegard LM, Towle TR, Kerns RJ, Hiasa H. Lentz SRC, et al. Biochimie. 2019 May;160:24-27. doi: 10.1016/j.biochi.2019.02.002. Epub 2019 Feb 11. Biochimie. 2019. PMID: 30763638 Free PMC article.

6

Interactions between Quinolones and Bacillus anthracis Gyrase and the Basis of Drug Resistance.

Ashley RE, Lindsey RH Jr, McPherson SA, Turnbough CL Jr, Kerns RJ, Osheroff N. Ashley RE, et al. Biochemistry. 2017 Aug 15;56(32):4191-4200. doi: 10.1021/acs.biochem.7b00203. Epub 2017 Aug 1. Biochemistry. 2017. PMID: 28708938 Free PMC article.

7

Identification of an ethyl 5,6-dihydropyrazolo[1,5-c]quinazoline-1-carboxylate as a catalytic inhibitor of DNA gyrase.

Aguirre AL, Chheda PR, Lentz SRC, Held HA, Groves NP, Hiasa H, Kerns RJ. Aguirre AL, et al. Bioorg Med Chem. 2020 May 15;28(10):115439. doi: 10.1016/j.bmc.2020.115439. Epub 2020 Mar 13. Bioorg Med Chem. 2020. PMID: 32234278 Free PMC article.

8

Fluoroquinolone-gyrase-DNA complexes: two modes of drug binding.

Mustaev A, Malik M, Zhao X, Kurepina N, Luan G, Oppegard LM, Hiasa H, Marks KR, Kerns RJ, Berger JM, Drlica K. Mustaev A, et al. J Biol Chem. 2014 May 2;289(18):12300-12. doi: 10.1074/jbc.M113.529164. Epub 2014 Feb 4. J Biol Chem. 2014. PMID: 24497635 Free PMC article.

9

Effect of N-1/c-8 ring fusion and C-7 ring structure on fluoroquinolone lethality.

Malik M, Marks KR, Schwanz HA, German N, Drlica K, Kerns RJ. Malik M, et al. Antimicrob Agents Chemother. 2010 Dec;54(12):5214-21. doi: 10.1128/AAC.01054-10. Epub 2010 Sep 20. Antimicrob Agents Chemother. 2010. PMID: 20855738 Free PMC article.

10

Resveratrol Antagonizes Antimicrobial Lethality and Stimulates Recovery of Bacterial Mutants.

Liu Y, Zhou J, Qu Y, Yang X, Shi G, Wang X, Hong Y, Drlica K, Zhao X. Liu Y, et al. PLoS One. 2016 Apr 5;11(4):e0153023. doi: 10.1371/journal.pone.0153023. eCollection 2016. PLoS One. 2016. PMID: 27045517 Free PMC article.

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