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Epigenetic changes and non-coding expanded repeats.
Nakamori M, Thornton C. Nakamori M, et al. Neurobiol Dis. 2010 Jul;39(1):21-7. doi: 10.1016/j.nbd.2010.02.004. Epub 2010 Feb 18. Neurobiol Dis. 2010. PMID: 20171282 Free PMC article. Review.
Myotonic dystrophy: RNA-mediated muscle disease.
Wheeler TM, Thornton CA. Wheeler TM, et al. Curr Opin Neurol. 2007 Oct;20(5):572-6. doi: 10.1097/WCO.0b013e3282ef6064. Curr Opin Neurol. 2007. PMID: 17885447 Review.
Triplet-repeat oligonucleotide-mediated reversal of RNA toxicity in myotonic dystrophy.
Mulders SA, van den Broek WJ, Wheeler TM, Croes HJ, van Kuik-Romeijn P, de Kimpe SJ, Furling D, Platenburg GJ, Gourdon G, Thornton CA, Wieringa B, Wansink DG. Mulders SA, et al. Proc Natl Acad Sci U S A. 2009 Aug 18;106(33):13915-20. doi: 10.1073/pnas.0905780106. Epub 2009 Aug 10. Proc Natl Acad Sci U S A. 2009. PMID: 19667189 Free PMC article.
Mexiletine is an effective antimyotonia treatment in myotonic dystrophy type 1.
Logigian EL, Martens WB, Moxley RT 4th, McDermott MP, Dilek N, Wiegner AW, Pearson AT, Barbieri CA, Annis CL, Thornton CA, Moxley RT 3rd. Logigian EL, et al. Neurology. 2010 May 4;74(18):1441-8. doi: 10.1212/WNL.0b013e3181dc1a3a. Neurology. 2010. PMID: 20439846 Free PMC article. Clinical Trial.
14 results