B20055/BB_/Biotechnology and Biological Sciences Research Council/United Kingdom[Grants and Funding] - Search Results

Year	Number of Results
2007	4
2008	2
2009	2
2010	1
2024	0

1

Dissecting the component reactions catalyzed by the actinorhodin minimal polyketide synthase.

Beltran-Alvarez P, Cox RJ, Crosby J, Simpson TJ. Beltran-Alvarez P, et al. Biochemistry. 2007 Dec 18;46(50):14672-81. doi: 10.1021/bi701784c. Epub 2007 Nov 23. Biochemistry. 2007. PMID: 18034463

2

Probing the Interactions of early polyketide intermediates with the Actinorhodin ACP from S. coelicolor A3(2).

Evans SE, Williams C, Arthur CJ, Płoskoń E, Wattana-amorn P, Cox RJ, Crosby J, Willis CL, Simpson TJ, Crump MP. Evans SE, et al. J Mol Biol. 2009 Jun 12;389(3):511-28. doi: 10.1016/j.jmb.2009.03.072. Epub 2009 Apr 8. J Mol Biol. 2009. PMID: 19361520

3

An ACP structural switch: conformational differences between the apo and holo forms of the actinorhodin polyketide synthase acyl carrier protein.

Evans SE, Williams C, Arthur CJ, Burston SG, Simpson TJ, Crosby J, Crump MP. Evans SE, et al. Chembiochem. 2008 Oct 13;9(15):2424-32. doi: 10.1002/cbic.200800180. Chembiochem. 2008. PMID: 18770515

4

A mammalian type I fatty acid synthase acyl carrier protein domain does not sequester acyl chains.

Ploskoń E, Arthur CJ, Evans SE, Williams C, Crosby J, Simpson TJ, Crump MP. Ploskoń E, et al. J Biol Chem. 2008 Jan 4;283(1):518-528. doi: 10.1074/jbc.M703454200. Epub 2007 Oct 30. J Biol Chem. 2008. PMID: 17971456 Free article.

5

Mutational analysis reveals that all tailoring region genes are required for production of polyketide antibiotic mupirocin by pseudomonas fluorescens: pseudomonic acid B biosynthesis precedes pseudomonic acid A.

Hothersall J, Wu J, Rahman AS, Shields JA, Haddock J, Johnson N, Cooper SM, Stephens ER, Cox RJ, Crosby J, Willis CL, Simpson TJ, Thomas CM. Hothersall J, et al. J Biol Chem. 2007 May 25;282(21):15451-61. doi: 10.1074/jbc.M701490200. Epub 2007 Mar 23. J Biol Chem. 2007. PMID: 17383964 Free article.

6

Recognition of intermediate functionality by acyl carrier protein over a complete cycle of fatty acid biosynthesis.

Płoskoń E, Arthur CJ, Kanari AL, Wattana-amorn P, Williams C, Crosby J, Simpson TJ, Willis CL, Crump MP. Płoskoń E, et al. Chem Biol. 2010 Jul 30;17(7):776-85. doi: 10.1016/j.chembiol.2010.05.024. Chem Biol. 2010. PMID: 20659690

7

Mupirocin H, a novel metabolite resulting from mutation of the HMG-CoA synthase analogue, mupH in Pseudomonas fluorescens.

Wu J, Cooper SM, Cox RJ, Crosby J, Crump MP, Hothersall J, Simpson TJ, Thomas CM, Willis CL. Wu J, et al. Chem Commun (Camb). 2007 May 28;(20):2040-2. doi: 10.1039/b700613f. Chem Commun (Camb). 2007. PMID: 17713071

8

Structure and malonyl CoA-ACP transacylase binding of streptomyces coelicolor fatty acid synthase acyl carrier protein.

Arthur CJ, Williams C, Pottage K, Płoskoń E, Findlow SC, Burston SG, Simpson TJ, Crump MP, Crosby J. Arthur CJ, et al. ACS Chem Biol. 2009 Aug 21;4(8):625-36. doi: 10.1021/cb900099e. ACS Chem Biol. 2009. PMID: 19555075

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