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Phosphoinositide lipids in primary cilia biology.
Conduit SE, Vanhaesebroeck B. Conduit SE, et al. Biochem J. 2020 Sep 30;477(18):3541-3565. doi: 10.1042/BCJ20200277. Biochem J. 2020. PMID: 32970140 Free PMC article. Review.
Somatostatin receptor 2 expression in nasopharyngeal cancer is induced by Epstein Barr virus infection: impact on prognosis, imaging and therapy.
Lechner M, Schartinger VH, Steele CD, Nei WL, Ooft ML, Schreiber LM, Pipinikas CP, Chung GT, Chan YY, Wu F, To KF, Tsang CM, Pearce W, Morelli D, Philpott M, Masterson L, Nibhani R, Wells G, Bell CG, Koller J, Delecluse S, Yip YL, Liu J, Forde CT, Forster MD, Jay A, Dudás J, Krapp A, Wan S, Uprimny C, Sprung S, Haybaeck J, Fenton TR, Chester K, Thirlwell C, Royle G, Marafioti T, Gupta R, Indrasari SR, Herdini C, Slim MAM, Indrawati I, Sutton L, Fles R, Tan B, Yeong J, Jain A, Han S, Wang H, Loke KSH, He W, Xu R, Jin H, Cheng Z, Howard D, Hwang PH, Le QT, Tay JK, West RB, Tsao SW, Meyer T, Riechelmann H, Oppermann U, Delecluse HJ, Willems SM, Chua MLK, Busson P, Lo KW, Wollmann G, Pillay N, Vanhaesebroeck B, Lund VJ. Lechner M, et al. Nat Commun. 2021 Jan 5;12(1):117. doi: 10.1038/s41467-020-20308-8. Nat Commun. 2021. PMID: 33402692 Free PMC article.
Enhanced antitumor immunity through sequential targeting of PI3Kδ and LAG3.
Lauder SN, Smart K, Kersemans V, Allen D, Scott J, Pires A, Milutinovic S, Somerville M, Smart S, Kinchesh P, Lopez-Guadamillas E, Hughes E, Jones E, Scurr M, Godkin A, Friedman LS, Vanhaesebroeck B, Gallimore A. Lauder SN, et al. J Immunother Cancer. 2020 Oct;8(2):e000693. doi: 10.1136/jitc-2020-000693. J Immunother Cancer. 2020. PMID: 33093155 Free PMC article.
p110δ PI3-Kinase Inhibition Perturbs APP and TNFα Trafficking, Reduces Plaque Burden, Dampens Neuroinflammation, and Prevents Cognitive Decline in an Alzheimer's Disease Mouse Model.
Martínez-Mármol R, Mohannak N, Qian L, Wang T, Gormal RS, Ruitenberg MJ, Vanhaesebroeck B, Coulson EJ, Meunier FA. Martínez-Mármol R, et al. J Neurosci. 2019 Oct 2;39(40):7976-7991. doi: 10.1523/JNEUROSCI.0674-19.2019. Epub 2019 Jul 30. J Neurosci. 2019. PMID: 31363064 Free PMC article.