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Page 1
The bortezomib/proteasome inhibitor PS-341 and triterpenoid CDDO-Im induce synergistic anti-multiple myeloma (MM) activity and overcome bortezomib resistance.
Chauhan D, Li G, Podar K, Hideshima T, Shringarpure R, Catley L, Mitsiades C, Munshi N, Tai YT, Suh N, Gribble GW, Honda T, Schlossman R, Richardson P, Sporn MB, Anderson KC. Chauhan D, et al. Blood. 2004 Apr 15;103(8):3158-66. doi: 10.1182/blood-2003-08-2873. Epub 2003 Dec 11. Blood. 2004. PMID: 15070698 Free article.
The triterpenoid CDDO induces apoptosis in refractory CLL B cells.
Pedersen IM, Kitada S, Schimmer A, Kim Y, Zapata JM, Charboneau L, Rassenti L, Andreeff M, Bennett F, Sporn MB, Liotta LD, Kipps TJ, Reed JC. Pedersen IM, et al. Blood. 2002 Oct 15;100(8):2965-72. doi: 10.1182/blood-2002-04-1174. Blood. 2002. PMID: 12351409 Free article.
Nrf2 is a critical modulator of the innate immune response in a model of uveitis.
Nagai N, Thimmulappa RK, Cano M, Fujihara M, Izumi-Nagai K, Kong X, Sporn MB, Kensler TW, Biswal S, Handa JT. Nagai N, et al. Free Radic Biol Med. 2009 Aug 1;47(3):300-6. doi: 10.1016/j.freeradbiomed.2009.04.033. Epub 2009 May 3. Free Radic Biol Med. 2009. PMID: 19410644 Free PMC article.
16 results