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Ink4a/Arf expression is a biomarker of aging.
Krishnamurthy J, Torrice C, Ramsey MR, Kovalev GI, Al-Regaiey K, Su L, Sharpless NE. Krishnamurthy J, et al. J Clin Invest. 2004 Nov;114(9):1299-307. doi: 10.1172/JCI22475. J Clin Invest. 2004. PMID: 15520862 Free PMC article.
CD200 is induced by ERK and is a potential therapeutic target in melanoma.
Petermann KB, Rozenberg GI, Zedek D, Groben P, McKinnon K, Buehler C, Kim WY, Shields JM, Penland S, Bear JE, Thomas NE, Serody JS, Sharpless NE. Petermann KB, et al. J Clin Invest. 2007 Dec;117(12):3922-9. doi: 10.1172/JCI32163. J Clin Invest. 2007. PMID: 18008004 Free PMC article.