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PCTAIRE1 phosphorylates p27 and regulates mitosis in cancer cells.

Yanagi T, Krajewska M, Matsuzawa S, Reed JC. Yanagi T, et al. Cancer Res. 2014 Oct 15;74(20):5795-807. doi: 10.1158/0008-5472.CAN-14-0872. Epub 2014 Sep 9. Cancer Res. 2014. PMID: 25205104 Free PMC article.

Siah1/SIP regulates p27(kip1) stability and cell migration under metabolic stress.

Nagano Y, Fukushima T, Okemoto K, Tanaka K, Bowtell DD, Ronai Z, Reed JC, Matsuzawa S. Nagano Y, et al. Cell Cycle. 2011 Aug 1;10(15):2592-602. doi: 10.4161/cc.10.15.16912. Epub 2011 Aug 1. Cell Cycle. 2011. PMID: 21734459 Free PMC article.

Critical function for SIP, a ubiquitin E3 ligase component of the beta-catenin degradation pathway, for thymocyte development and G1 checkpoint.

Fukushima T, Zapata JM, Singha NC, Thomas M, Kress CL, Krajewska M, Krajewski S, Ronai Z, Reed JC, Matsuzawa S. Fukushima T, et al. Immunity. 2006 Jan;24(1):29-39. doi: 10.1016/j.immuni.2005.12.002. Immunity. 2006. PMID: 16413921 Free article.

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