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Isoliquiritigenin induces apoptosis and inhibits xenograft tumor growth of human lung cancer cells by targeting both wild type and L858R/T790M mutant EGFR.
J Biol Chem. 2014 Dec 26;289(52):35839-48. doi: 10.1074/jbc.M114.585513. Epub 2014 Nov 3.
J Biol Chem. 2014.
PMID: 25368326
Free PMC article.
Cyclin-dependent kinase 2 (CDK2) is a key mediator for EGF-induced cell transformation mediated through the ELK4/c-Fos signaling pathway.
Peng C, Zeng W, Su J, Kuang Y, He Y, Zhao S, Zhang J, Ma W, Bode AM, Dong Z, Chen X.
Peng C, et al.
Oncogene. 2016 Mar 3;35(9):1170-9. doi: 10.1038/onc.2015.175. Epub 2015 Jun 1.
Oncogene. 2016.
PMID: 26028036
Free PMC article.
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