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Why do patients with cancer die?
Boire A, Burke K, Cox TR, Guise T, Jamal-Hanjani M, Janowitz T, Kaplan R, Lee R, Swanton C, Vander Heiden MG, Sahai E. Boire A, et al. Nat Rev Cancer. 2024 Aug;24(8):578-589. doi: 10.1038/s41568-024-00708-4. Epub 2024 Jun 19. Nat Rev Cancer. 2024. PMID: 38898221 Free PMC article. Review.
Spatial Architecture of Myeloid and T Cells Orchestrates Immune Evasion and Clinical Outcome in Lung Cancer.
Enfield KSS, Colliver E, Lee C, Magness A, Moore DA, Sivakumar M, Grigoriadis K, Pich O, Karasaki T, Hobson PS, Levi D, Veeriah S, Puttick C, Nye EL, Green M, Dijkstra KK, Shimato M, Akarca AU, Marafioti T, Salgado R, Hackshaw A; TRACERx consortium; Jamal-Hanjani M, van Maldegem F, McGranahan N, Glass B, Pulaski H, Walk E, Reading JL, Quezada SA, Hiley CT, Downward J, Sahai E, Swanton C, Angelova M. Enfield KSS, et al. Cancer Discov. 2024 Jun 3;14(6):1018-1047. doi: 10.1158/2159-8290.CD-23-1380. Cancer Discov. 2024. PMID: 38581685 Free PMC article.
Oncogenic PIK3CA corrupts growth factor signaling specificity.
Madsen RR, Le Marois A, Mruk ON, Voliotis M, Yin S, Sufi J, Qin X, Zhao SJ, Gorczynska J, Morelli D, Davidson L, Sahai E, Korolchuk VI, Tape CJ, Vanhaesebroeck B. Madsen RR, et al. Mol Syst Biol. 2024 Dec 20. doi: 10.1038/s44320-024-00078-x. Online ahead of print. Mol Syst Biol. 2024. PMID: 39706867 Free article.