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The Mediator complex and transcription regulation.
Poss ZC, Ebmeier CC, Taatjes DJ. Poss ZC, et al. Crit Rev Biochem Mol Biol. 2013 Nov-Dec;48(6):575-608. doi: 10.3109/10409238.2013.840259. Epub 2013 Oct 3. Crit Rev Biochem Mol Biol. 2013. PMID: 24088064 Free PMC article. Review.
Mediator kinase inhibition further activates super-enhancer-associated genes in AML.
Pelish HE, Liau BB, Nitulescu II, Tangpeerachaikul A, Poss ZC, Da Silva DH, Caruso BT, Arefolov A, Fadeyi O, Christie AL, Du K, Banka D, Schneider EV, Jestel A, Zou G, Si C, Ebmeier CC, Bronson RT, Krivtsov AV, Myers AG, Kohl NE, Kung AL, Armstrong SA, Lemieux ME, Taatjes DJ, Shair MD. Pelish HE, et al. Nature. 2015 Oct 8;526(7572):273-276. doi: 10.1038/nature14904. Epub 2015 Sep 28. Nature. 2015. PMID: 26416749 Free PMC article.