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Fibrils colocalize caspase-3 with procaspase-3 to foster maturation.
J Biol Chem. 2012 Sep 28;287(40):33781-95. doi: 10.1074/jbc.M112.386128. Epub 2012 Aug 7.
J Biol Chem. 2012.
PMID: 22872644
Free PMC article.
Self-assembling small molecules form nanofibrils that bind procaspase-3 to promote activation.
Zorn JA, Wille H, Wolan DW, Wells JA.
Zorn JA, et al.
J Am Chem Soc. 2011 Dec 14;133(49):19630-3. doi: 10.1021/ja208350u. Epub 2011 Nov 17.
J Am Chem Soc. 2011.
PMID: 22066605
Free PMC article.
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Small-molecule activators of a proenzyme.
Wolan DW, Zorn JA, Gray DC, Wells JA.
Wolan DW, et al.
Science. 2009 Nov 6;326(5954):853-8. doi: 10.1126/science.1177585.
Science. 2009.
PMID: 19892984
Free PMC article.
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