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The Piezo channel is a mechano-sensitive complex component in the mammalian inner ear hair cell.
Lee JH, Perez-Flores MC, Park S, Kim HJ, Chen Y, Kang M, Kersigo J, Choi J, Thai PN, Woltz RL, Perez-Flores DC, Perkins G, Sihn CR, Trinh P, Zhang XD, Sirish P, Dong Y, Feng WW, Pessah IN, Dixon RE, Sokolowski B, Fritzsch B, Chiamvimonvat N, Yamoah EN. Lee JH, et al. Nat Commun. 2024 Jan 16;15(1):526. doi: 10.1038/s41467-023-44230-x. Nat Commun. 2024. PMID: 38228630 Free PMC article.
Atomistic mechanisms of the regulation of small-conductance Ca2+-activated K+ channel (SK2) by PIP2.
Woltz RL, Zheng Y, Choi W, Ngo K, Trinh P, Ren L, Thai PN, Harris BJ, Han Y, Rouen KC, Mateos DL, Jian Z, Chen-Izu Y, Dickson EJ, Yamoah EN, Yarov-Yarovoy V, Vorobyov I, Zhang XD, Chiamvimonvat N. Woltz RL, et al. Proc Natl Acad Sci U S A. 2024 Sep 24;121(39):e2318900121. doi: 10.1073/pnas.2318900121. Epub 2024 Sep 17. Proc Natl Acad Sci U S A. 2024. PMID: 39288178 Free PMC article.