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Impact of gene polymorphisms involved in the vitamin D metabolic pathway on the susceptibility to and severity of autism spectrum disorder.
Saechua C, Sarachana T, Chonchaiya W, Trairatvorakul P, Yuwattana W, Poolcharoen C, Sangritdech M, Saeliw T, van Erp ML, Sangsuthum S, Akarapredee N, Tipnoppanon S, Sukprasong R, Satapornpong P, Atasilp C, Sukasem C, Vanwong N. Saechua C, et al. Sci Rep. 2024 Nov 16;14(1):28333. doi: 10.1038/s41598-024-79994-9. Sci Rep. 2024. PMID: 39550459 Free PMC article.
An Ultrasound-Triggered STING Pathway Nanoagonist for Enhanced Chemotherapy-Induced Immunogenic Cell Death.
Tian Y, Tian H, Li B, Feng C, Dai Y. Tian Y, et al. Small. 2024 Jun;20(26):e2309850. doi: 10.1002/smll.202309850. Epub 2024 Jan 15. Small. 2024. PMID: 38225710
Subsequently, both the dsDNA and zinc ions bind with cyclic GMP-AMP synthase and activate the stimulator of interferon genes (STING) pathway, resulting in the dendritic cell maturation, ultimately promoting DOX-induced ICD effects and antigen-specific T cell immunity. ...
Subsequently, both the dsDNA and zinc ions bind with cyclic GMP-AMP synthase and activate the stimulator of interferon genes (STING) …
PhotoPyro-Induced cGAS-STING Pathway Activation Enhanced Anti-Melanoma Immunotherapy via a Manganese-Coordinated Nanomedicine.
Feng Y, Wang G, Li W, Yan J, Yu X, Tian H, Li B, Dai Y. Feng Y, et al. Adv Healthc Mater. 2024 Mar;13(6):e2302811. doi: 10.1002/adhm.202302811. Epub 2023 Nov 15. Adv Healthc Mater. 2024. PMID: 37909376
Simultaneously, photoirradiation-triggered double-stranded DNA generation in the cytosol would activate the Mn(2+) -sensitized cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) pathway, which further augment the PhotoPyro-induced immune response. ...
Simultaneously, photoirradiation-triggered double-stranded DNA generation in the cytosol would activate the Mn(2+) -sensitized cyclic GMP- …