Near-Universal Resistance to Macrolides of Treponema pallidum in North America

N Engl J Med. 2024 Jun 13;390(22):2127-2128. doi: 10.1056/NEJMc2314441.
No abstract available

Publication types

  • Letter

MeSH terms

  • Anti-Bacterial Agents* / pharmacology
  • Anti-Bacterial Agents* / supply & distribution
  • Anti-Bacterial Agents* / therapeutic use
  • Azithromycin* / pharmacology
  • Azithromycin* / therapeutic use
  • Canada
  • Doxycycline / pharmacology
  • Doxycycline / supply & distribution
  • Doxycycline / therapeutic use
  • Drug Resistance, Bacterial* / genetics
  • Humans
  • Macrolides* / pharmacology
  • Macrolides* / therapeutic use
  • North America
  • Penicillin G Benzathine / pharmacology
  • Penicillin G Benzathine / supply & distribution
  • Penicillin G Benzathine / therapeutic use
  • Syphilis* / drug therapy
  • Syphilis* / genetics
  • Syphilis* / microbiology
  • Treponema pallidum* / drug effects
  • Treponema pallidum* / genetics
  • Treponema pallidum* / isolation & purification
  • United States

Substances

  • Anti-Bacterial Agents
  • Macrolides
  • Azithromycin
  • Penicillin G Benzathine
  • Doxycycline