I 2306/FWF_/Austrian Science Fund FWF/Austria[Grants and Funding] - Search Results

Year	Number of Results
2017	1
2018	3
2019	2
2020	1
2022	1
2024	0

1

α6-Containing GABA_A Receptors: Functional Roles and Therapeutic Potentials.

Sieghart W, Chiou LC, Ernst M, Fabjan J, M Savić M, Lee MT. Sieghart W, et al. Pharmacol Rev. 2022 Jan;74(1):238-270. doi: 10.1124/pharmrev.121.000293. Pharmacol Rev. 2022. PMID: 35017178 Review.

2

Two Distinct Populations of α1α6-Containing GABAA-Receptors in Rat Cerebellum.

Scholze P, Pökl M, Längle S, Steudle F, Fabjan J, Ernst M. Scholze P, et al. Front Synaptic Neurosci. 2020 Oct 6;12:591129. doi: 10.3389/fnsyn.2020.591129. eCollection 2020. Front Synaptic Neurosci. 2020. PMID: 33123001 Free PMC article.

3

Trigeminal neuropathic pain development and maintenance in rats are suppressed by a positive modulator of α6 GABA_A receptors.

Vasović D, Divović B, Treven M, Knutson DE, Steudle F, Scholze P, Obradović A, Fabjan J, Brković B, Sieghart W, Ernst M, Cook JM, Savić MM. Vasović D, et al. Eur J Pain. 2019 May;23(5):973-984. doi: 10.1002/ejp.1365. Epub 2019 Feb 4. Eur J Pain. 2019. PMID: 30633839 Free PMC article.

4

The α6 subunit-containing GABA_A receptor: A novel drug target for inhibition of trigeminal activation.

Fan PC, Lai TH, Hor CC, Lee MT, Huang P, Sieghart W, Ernst M, Knutson DE, Cook J, Chiou LC. Fan PC, et al. Neuropharmacology. 2018 Sep 15;140:1-13. doi: 10.1016/j.neuropharm.2018.07.017. Epub 2018 Jul 21. Neuropharmacology. 2018. PMID: 30016665 Free PMC article.

5

Towards functional selectivity for α6β3γ2 GABA_A receptors: a series of novel pyrazoloquinolinones.

Treven M, Siebert DCB, Holzinger R, Bampali K, Fabjan J, Varagic Z, Wimmer L, Steudle F, Scholze P, Schnürch M, Mihovilovic MD, Ernst M. Treven M, et al. Br J Pharmacol. 2018 Feb;175(3):419-428. doi: 10.1111/bph.14087. Epub 2017 Dec 22. Br J Pharmacol. 2018. PMID: 29127702 Free PMC article.

6

Defined concatenated α6α1β3γ2 GABA_A receptor constructs reveal dual action of pyrazoloquinolinone allosteric modulators.

Simeone X, Iorio MT, Siebert DCB, Rehman S, Schnürch M, Mihovilovic MD, Ernst M. Simeone X, et al. Bioorg Med Chem. 2019 Jul 15;27(14):3167-3178. doi: 10.1016/j.bmc.2019.06.006. Epub 2019 Jun 5. Bioorg Med Chem. 2019. PMID: 31186146

7

Design and Synthesis of Novel Deuterated Ligands Functionally Selective for the γ-Aminobutyric Acid Type A Receptor (GABA_AR) α6 Subtype with Improved Metabolic Stability and Enhanced Bioavailability.

Knutson DE, Kodali R, Divović B, Treven M, Stephen MR, Zahn NM, Dobričić V, Huber AT, Meirelles MA, Verma RS, Wimmer L, Witzigmann C, Arnold LA, Chiou LC, Ernst M, Mihovilovic MD, Savić MM, Sieghart W, Cook JM. Knutson DE, et al. J Med Chem. 2018 Mar 22;61(6):2422-2446. doi: 10.1021/acs.jmedchem.7b01664. Epub 2018 Mar 6. J Med Chem. 2018. PMID: 29481759 Free PMC article.

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