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Microglial senescence contributes to female-biased neuroinflammation in the aging mouse hippocampus: implications for Alzheimer's disease.
Ocañas SR, Pham KD, Cox JEJ, Keck AW, Ko S, Ampadu FA, Porter HL, Ansere VA, Kulpa A, Kellogg CM, Machalinski AH, Thomas MA, Wright Z, Chucair-Elliott AJ, Freeman WM. Ocañas SR, et al. J Neuroinflammation. 2023 Aug 16;20(1):188. doi: 10.1186/s12974-023-02870-2. J Neuroinflammation. 2023. PMID: 37587511 Free PMC article.
VTA dopamine neurons are hyperexcitable in 3xTg-AD mice due to casein kinase 2-dependent SK channel dysfunction.
Blankenship HE, Carter KA, Cassidy NT, Markiewicz AN, Thellmann MI, Sharpe AL, Freeman WM, Beckstead MJ. Blankenship HE, et al. bioRxiv [Preprint]. 2023 Nov 17:2023.11.16.567486. doi: 10.1101/2023.11.16.567486. bioRxiv. 2023. Update in: Nat Commun. 2024 Nov 8;15(1):9673. doi: 10.1038/s41467-024-53891-1 PMID: 38014232 Free PMC article. Updated. Preprint.
Microglial senescence contributes to female-biased neuroinflammation in the aging mouse hippocampus: implications for Alzheimer's disease.
Ocañas SR, Pham KD, Cox JEJ, Keck AW, Ko S, Ampadu FA, Porter HL, Ansere VA, Kulpa A, Kellogg CM, Machalinski AH, Chucair-Elliott AJ, Freeman WM. Ocañas SR, et al. bioRxiv [Preprint]. 2023 Jun 1:2023.03.07.531562. doi: 10.1101/2023.03.07.531562. bioRxiv. 2023. Update in: J Neuroinflammation. 2023 Aug 16;20(1):188. doi: 10.1186/s12974-023-02870-2 PMID: 36945656 Free PMC article. Updated. Preprint.
Microglial MHC-I induction with aging and Alzheimer's is conserved in mouse models and humans.
Kellogg CM, Pham K, Machalinski AH, Porter HL, Blankenship HE, Tooley K, Stout MB, Rice HC, Sharpe AL, Beckstead MJ, Chucair-Elliott AJ, Ocañas SR, Freeman WM. Kellogg CM, et al. bioRxiv [Preprint]. 2023 Jun 2:2023.03.07.531435. doi: 10.1101/2023.03.07.531435. bioRxiv. 2023. Update in: Geroscience. 2023 Oct;45(5):3019-3043. doi: 10.1007/s11357-023-00859-6 PMID: 36945372 Free PMC article. Updated. Preprint.
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