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Dual inhibition of SUMOylation and MEK conquers MYC-expressing KRAS-mutant cancers by accumulating DNA damage.

Kotani H, Oshima H, Boucher JC, Yamano T, Sakaguchi H, Sato S, Fukuda K, Nishiyama A, Yamashita K, Ohtsubo K, Takeuchi S, Nishiuchi T, Oshima M, Davila ML, Yano S. Kotani H, et al. J Biomed Sci. 2024 Jul 11;31(1):68. doi: 10.1186/s12929-024-01060-3. J Biomed Sci. 2024. PMID: 38992694 Free PMC article.

Comprehensive antitumor immune response boosted by dual inhibition of SUMOylation and MEK in MYC-expressing KRAS-mutant cancers.

Kotani H, Yamano T, Boucher JC, Sato S, Sakaguchi H, Fukuda K, Nishiyama A, Yamashita K, Ohtsubo K, Takeuchi S, Nishiuchi T, Oshima H, Oshima M, Davila ML, Yano S. Kotani H, et al. Exp Hematol Oncol. 2024 Sep 27;13(1):94. doi: 10.1186/s40164-024-00563-x. Exp Hematol Oncol. 2024. PMID: 39334463 Free PMC article.

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