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Page 1
Hypertension: Do Inflammation and Immunity Hold the Key to Solving this Epidemic?
Madhur MS, Elijovich F, Alexander MR, Pitzer A, Ishimwe J, Van Beusecum JP, Patrick DM, Smart CD, Kleyman TR, Kingery J, Peck RN, Laffer CL, Kirabo A. Madhur MS, et al. Circ Res. 2021 Apr 2;128(7):908-933. doi: 10.1161/CIRCRESAHA.121.318052. Epub 2021 Apr 1. Circ Res. 2021. PMID: 33793336 Free PMC article. Review.
The role of inflammation in hypertension: novel concepts.
Patrick DM, Van Beusecum JP, Kirabo A. Patrick DM, et al. Curr Opin Physiol. 2021 Feb;19:92-98. doi: 10.1016/j.cophys.2020.09.016. Epub 2020 Oct 13. Curr Opin Physiol. 2021. PMID: 33073072 Free PMC article. Review.
DC ENaC-Dependent Inflammasome Activation Contributes to Salt-Sensitive Hypertension.
Pitzer A, Elijovich F, Laffer CL, Ertuglu LA, Sahinoz M, Saleem M, Krishnan J, Dola T, Aden LA, Sheng Q, Raddatz MA, Wanjalla C, Pakala S, Davies SS, Patrick DM, Kon V, Ikizler TA, Kleyman T, Kirabo A. Pitzer A, et al. Circ Res. 2022 Aug 5;131(4):328-344. doi: 10.1161/CIRCRESAHA.122.320818. Epub 2022 Jul 12. Circ Res. 2022. PMID: 35862128 Free PMC article.
Isolevuglandins disrupt PU.1-mediated C1q expression and promote autoimmunity and hypertension in systemic lupus erythematosus.
Patrick DM, de la Visitación N, Krishnan J, Chen W, Ormseth MJ, Stein CM, Davies SS, Amarnath V, Crofford LJ, Williams JM, Zhao S, Smart CD, Dikalov S, Dikalova A, Xiao L, Van Beusecum JP, Ao M, Fogo AB, Kirabo A, Harrison DG. Patrick DM, et al. JCI Insight. 2022 Jul 8;7(13):e136678. doi: 10.1172/jci.insight.136678. JCI Insight. 2022. PMID: 35608913 Free PMC article.
Role of Axl in target organ inflammation and damage due to hypertensive aortic remodeling.
Chen W, Van Beusecum JP, Xiao L, Patrick DM, Ao M, Zhao S, Lopez MG, Billings FT 4th, Cavinato C, Caulk AW, Humphrey JD, Harrison DG. Chen W, et al. Am J Physiol Heart Circ Physiol. 2022 Nov 1;323(5):H917-H933. doi: 10.1152/ajpheart.00253.2022. Epub 2022 Sep 9. Am J Physiol Heart Circ Physiol. 2022. PMID: 36083796 Free PMC article.
Posttranslationally modified self-peptides promote hypertension in mouse models.
Bloodworth N, Chen W, Hunter K, Patrick D, Palubinsky A, Phillips E, Roeth D, Kalkum M, Mallal S, Davies S, Ao M, Moretti R, Meiler J, Harrison DG. Bloodworth N, et al. J Clin Invest. 2024 Aug 15;134(16):e174374. doi: 10.1172/JCI174374. J Clin Invest. 2024. PMID: 39145457 Free PMC article.
Growth Arrest Specific-6 and Axl Coordinate Inflammation and Hypertension.
Van Beusecum JP, Barbaro NR, Smart CD, Patrick DM, Loperena R, Zhao S, de la Visitacion N, Ao M, Xiao L, Shibao CA, Harrison DG. Van Beusecum JP, et al. Circ Res. 2021 Nov 12;129(11):975-991. doi: 10.1161/CIRCRESAHA.121.319643. Epub 2021 Sep 27. Circ Res. 2021. PMID: 34565181 Free PMC article.