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A genome-wide association study of the human metabolome in a community-based cohort.
Rhee EP, Ho JE, Chen MH, Shen D, Cheng S, Larson MG, Ghorbani A, Shi X, Helenius IT, O'Donnell CJ, Souza AL, Deik A, Pierce KA, Bullock K, Walford GA, Vasan RS, Florez JC, Clish C, Yeh JR, Wang TJ, Gerszten RE. Rhee EP, et al. Cell Metab. 2013 Jul 2;18(1):130-43. doi: 10.1016/j.cmet.2013.06.013. Cell Metab. 2013. PMID: 23823483 Free PMC article.
Metabolomics and renal disease.
Rhee EP. Rhee EP. Curr Opin Nephrol Hypertens. 2015 Jul;24(4):371-9. doi: 10.1097/MNH.0000000000000136. Curr Opin Nephrol Hypertens. 2015. PMID: 26050125 Free PMC article. Review.
Distinct metabolomic signatures are associated with longevity in humans.
Cheng S, Larson MG, McCabe EL, Murabito JM, Rhee EP, Ho JE, Jacques PF, Ghorbani A, Magnusson M, Souza AL, Deik AA, Pierce KA, Bullock K, O'Donnell CJ, Melander O, Clish CB, Vasan RS, Gerszten RE, Wang TJ. Cheng S, et al. Nat Commun. 2015 Apr 13;6:6791. doi: 10.1038/ncomms7791. Nat Commun. 2015. PMID: 25864806 Free PMC article.
A combined epidemiologic and metabolomic approach improves CKD prediction.
Rhee EP, Clish CB, Ghorbani A, Larson MG, Elmariah S, McCabe E, Yang Q, Cheng S, Pierce K, Deik A, Souza AL, Farrell L, Domos C, Yeh RW, Palacios I, Rosenfield K, Vasan RS, Florez JC, Wang TJ, Fox CS, Gerszten RE. Rhee EP, et al. J Am Soc Nephrol. 2013 Jul;24(8):1330-8. doi: 10.1681/ASN.2012101006. Epub 2013 May 16. J Am Soc Nephrol. 2013. PMID: 23687356 Free PMC article.