Abstract
Muscle pain is a prevalent clinical problem but can be difficult to treat because relatively little is known about nervous system mechanisms that mediate and modulate it. This review profiles four new animal models of muscle and deep tissue pain currently being used to elucidate mechanisms of muscle pain and analgesia.
Publication types
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Research Support, U.S. Gov't, P.H.S.
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Review
MeSH terms
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Acid-Base Imbalance / complications
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Adaptation, Physiological / physiology
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Animals
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Carrageenan
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Disease Models, Animal*
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Hyperalgesia / chemically induced
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Hyperalgesia / physiopathology*
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Hyperalgesia / therapy
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Mice
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Movement / physiology
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Muscle, Skeletal / physiopathology*
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Neoplasms / complications
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Pain / etiology
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Pain / physiopathology*
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Pain Management
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Pain Threshold / physiology
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Physical Conditioning, Animal / adverse effects
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Physical Conditioning, Animal / physiology
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Rats