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Racial or ethnic differences in allele frequencies of single-nucleotide polymorphisms in the methylenetetrahydrofolate reductase gene and their influence on response to methotrexate in rheumatoid arthritis.
Hughes LB, Beasley TM, Patel H, Tiwari HK, Morgan SL, Baggott JE, Saag KG, McNicholl J, Moreland LW, Alarcón GS, Bridges SL Jr. Hughes LB, et al. Ann Rheum Dis. 2006 Sep;65(9):1213-8. doi: 10.1136/ard.2005.046797. Epub 2006 Jan 26. Ann Rheum Dis. 2006. PMID: 16439441 Free PMC article.
The HLA-DRB1 shared epitope is associated with susceptibility to rheumatoid arthritis in African Americans through European genetic admixture.
Hughes LB, Morrison D, Kelley JM, Padilla MA, Vaughan LK, Westfall AO, Dwivedi H, Mikuls TR, Holers VM, Parrish LA, Alarcón GS, Conn DL, Jonas BL, Callahan LF, Smith EA, Gilkeson GS, Howard G, Moreland LW, Patterson N, Reich D, Bridges SL Jr. Hughes LB, et al. Arthritis Rheum. 2008 Feb;58(2):349-58. doi: 10.1002/art.23166. Arthritis Rheum. 2008. PMID: 18240241 Free PMC article.