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Tertiary lymphoid structures in desmoplastic melanoma have increased lymphocyte density, lymphocyte proliferation, and immune cross talk with tumor when compared to non-desmoplastic melanomas.
Edmonds NL, Gradecki SE, Katyal P, Lynch KT, Stowman AM, Gru AA, Engelhard VH, Slingluff CL Jr, Mauldin IS. Edmonds NL, et al. Oncoimmunology. 2023 Jan 7;12(1):2164476. doi: 10.1080/2162402X.2022.2164476. eCollection 2023. Oncoimmunology. 2023. PMID: 36632563 Free PMC article.
Trial to evaluate the immunogenicity and safety of a melanoma helper peptide vaccine plus incomplete Freund's adjuvant, cyclophosphamide, and polyICLC (Mel63).
Slingluff CL Jr, Petroni GR, Chianese-Bullock KA, Wages NA, Olson WC, Smith KT, Haden K, Dengel LT, Dickinson A, Reed C, Gaughan EM, Grosh WW, Kaur V, Varhegyi N, Smolkin M, Galeassi NV, Deacon D, Hall EH. Slingluff CL Jr, et al. J Immunother Cancer. 2021 Jan;9(1):e000934. doi: 10.1136/jitc-2020-000934. J Immunother Cancer. 2021. PMID: 33479025 Free PMC article. Clinical Trial.
30 results