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Ovarian cancer immunogenicity is governed by a narrow subset of progenitor tissue-resident memory T cells.
Anadon CM, Yu X, Hänggi K, Biswas S, Chaurio RA, Martin A, Payne KK, Mandal G, Innamarato P, Harro CM, Mine JA, Sprenger KB, Cortina C, Powers JJ, Costich TL, Perez BA, Gatenbee CD, Prabhakaran S, Marchion D, Heemskerk MHM, Curiel TJ, Anderson AR, Wenham RM, Rodriguez PC, Conejo-Garcia JR. Anadon CM, et al. Cancer Cell. 2022 May 9;40(5):545-557.e13. doi: 10.1016/j.ccell.2022.03.008. Epub 2022 Apr 14. Cancer Cell. 2022. PMID: 35427494 Free PMC article.
Targeting intracellular oncoproteins with dimeric IgA promotes expulsion from the cytoplasm and immune-mediated control of epithelial cancers.
Biswas S, Mandal G, Anadon CM, Chaurio RA, Lopez-Bailon LU, Nagy MZ, Mine JA, Hänggi K, Sprenger KB, Innamarato P, Harro CM, Powers JJ, Johnson J, Fang B, Eysha M, Nan X, Li R, Perez BA, Curiel TJ, Yu X, Rodriguez PC, Conejo-Garcia JR. Biswas S, et al. Immunity. 2023 Nov 14;56(11):2570-2583.e6. doi: 10.1016/j.immuni.2023.09.013. Epub 2023 Oct 30. Immunity. 2023. PMID: 37909039 Free PMC article.
Sézary syndrome originates from heavily mutated hematopoietic progenitors.
Harro CM, Sprenger KB, Chaurio RA, Powers JJ, Innamarato P, Anadon CM, Zhang Y, Biswas S, Mandal G, Mine JA, Cortina C, Nagy MZ, Martin AL, Handley KF, Borjas GJ, Chen PL, Pinilla-Ibarz J, Sokol L, Yu X, Conejo-Garcia JR. Harro CM, et al. Blood Adv. 2023 Sep 26;7(18):5586-5602. doi: 10.1182/bloodadvances.2022008562. Blood Adv. 2023. PMID: 37531660 Free PMC article.
Actionable spontaneous antibody responses antagonize malignant progression in ovarian carcinoma.
Handley KF, Mehta S, Martin AL, Biswas S, Maharaj K, Nagy MZ, Mine JA, Cortina C, Yu X, Sprenger K, Mandal G, Innamarato P, Powers JJ, Harro CM, Chaurio RA, Anadon CM, Shahzad MM, Flores I, Conejo-Garcia JR. Handley KF, et al. Gynecol Oncol. 2023 Jun;173:114-121. doi: 10.1016/j.ygyno.2023.03.020. Epub 2023 Apr 28. Gynecol Oncol. 2023. PMID: 37121178 Free PMC article.
Olfactory Receptor OR2H1 Is an Effective Target for CAR T Cells in Human Epithelial Tumors.
Martin AL, Anadon CM, Biswas S, Mine JA, Handley KF, Payne KK, Mandal G, Chaurio RA, Powers JJ, Sprenger KB, Rigolizzo KE, Innamarato P, Harro CM, Mehta S, Perez BA, Wenham RM, Conejo-Garcia JR. Martin AL, et al. Mol Cancer Ther. 2022 Jul 5;21(7):1184-1194. doi: 10.1158/1535-7163.MCT-21-0872. Mol Cancer Ther. 2022. PMID: 35499393 Free PMC article.