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Human alveolar type 2 epithelium transdifferentiates into metaplastic KRT5+ basal cells.
Nat Cell Biol. 2022 Jan;24(1):10-23. doi: 10.1038/s41556-021-00809-4. Epub 2021 Dec 30.
Nat Cell Biol. 2022.
PMID: 34969962
Free PMC article.
Human distal airways contain a multipotent secretory cell that can regenerate alveoli.
Basil MC, Cardenas-Diaz FL, Kathiriya JJ, Morley MP, Carl J, Brumwell AN, Katzen J, Slovik KJ, Babu A, Zhou S, Kremp MM, McCauley KB, Li S, Planer JD, Hussain SS, Liu X, Windmueller R, Ying Y, Stewart KM, Oyster M, Christie JD, Diamond JM, Engelhardt JF, Cantu E, Rowe SM, Kotton DN, Chapman HA, Morrisey EE.
Basil MC, et al.
Nature. 2022 Apr;604(7904):120-126. doi: 10.1038/s41586-022-04552-0. Epub 2022 Mar 30.
Nature. 2022.
PMID: 35355013
Free PMC article.
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BCL-2 Modulates IRE1α Activation to Attenuate Endoplasmic Reticulum Stress and Pulmonary Fibrosis.
Le Saux CJ, Ho TC, Brumwell AM, Kathiriya JJ, Wei Y, Hughes JB, Garakani K, Atabai K, Auyeung VC, Papa FR, Chapman HA.
Le Saux CJ, et al.
Am J Respir Cell Mol Biol. 2024 Apr;70(4):247-258. doi: 10.1165/rcmb.2023-0109OC.
Am J Respir Cell Mol Biol. 2024.
PMID: 38117250
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