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Enhancing mitochondrial pyruvate metabolism ameliorates myocardial ischemic reperfusion injury.
Visker JR, Cluntun AA, Velasco-Silva JN, Eberhardt DR, Shankar TS, Hamouche R, Ling J, Kwak H, Hillas Y, Aist I, Tseliou E, Navankasattusas S, Chaudhuri D, Ducker GS, Drakos SG, Rutter J. Visker JR, et al. bioRxiv [Preprint]. 2024 Feb 4:2024.02.01.577463. doi: 10.1101/2024.02.01.577463. bioRxiv. 2024. Update in: JCI Insight. 2024 Jul 25;9(17):e180906. doi: 10.1172/jci.insight.180906. PMID: 38352459 Free PMC article. Updated. Preprint.
Direct mitochondrial import of lactate supports resilient carbohydrate oxidation.
Cluntun AA, Visker JR, Velasco-Silva JN, Lang MJ, Cedeño-Rosario L, Shankar TS, Hamouche R, Ling J, Kim JE, Toshniwal AG, Low HK, Cunningham CN, Carrington J, Catrow JL, Pearce Q, Jeong MY, Bott AJ, Narbona-Pérez ÁJ, Stanley CE, Li Q, Eberhardt DR, Morgan JT, Yadav T, Wells CE, Ramadurai DKA, Swiatek WI, Chaudhuri D, Rothstein JD, Muoio DM, Paulo JA, Gygi SP, Baker SA, Navankasattusas S, Cox JE, Funai K, Drakos SG, Rutter J, Ducker GS. Cluntun AA, et al. bioRxiv [Preprint]. 2024 Oct 8:2024.10.07.617073. doi: 10.1101/2024.10.07.617073. bioRxiv. 2024. PMID: 39416192 Free PMC article. Preprint.