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Sperm selection with hyaluronic acid improved live birth outcomes among older couples and was connected to sperm DNA quality, potentially affecting all treatment outcomes.
West R, Coomarasamy A, Frew L, Hutton R, Kirkman-Brown J, Lawlor M, Lewis S, Partanen R, Payne-Dwyer A, Román-Montañana C, Torabi F, Tsagdi S, Miller D. West R, et al. Hum Reprod. 2022 May 30;37(6):1106-1125. doi: 10.1093/humrep/deac058. Hum Reprod. 2022. PMID: 35459947 Free PMC article.
Physiological, hyaluronan-selected intracytoplasmic sperm injection for infertility treatment (HABSelect): a parallel, two-group, randomised trial.
Miller D, Pavitt S, Sharma V, Forbes G, Hooper R, Bhattacharya S, Kirkman-Brown J, Coomarasamy A, Lewis S, Cutting R, Brison D, Pacey A, West R, Brian K, Griffin D, Khalaf Y. Miller D, et al. Lancet. 2019 Feb 2;393(10170):416-422. doi: 10.1016/S0140-6736(18)32989-1. Lancet. 2019. PMID: 30712901 Free PMC article. Clinical Trial.
Hyaluronic Acid Binding Sperm Selection for assisted reproduction treatment (HABSelect): study protocol for a multicentre randomised controlled trial.
Witt KD, Beresford L, Bhattacharya S, Brian K, Coomarasamy A, Cutting R, Hooper R, Kirkman-Brown J, Khalaf Y, Lewis SE, Pacey A, Pavitt S, West R, Miller D, Cutting R. Witt KD, et al. BMJ Open. 2016 Oct 7;6(10):e012609. doi: 10.1136/bmjopen-2016-012609. BMJ Open. 2016. PMID: 27855103 Free PMC article. Clinical Trial.