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Iron dysregulation and inflammatory stress erythropoiesis associates with long-term outcome of COVID-19.
Hanson AL, Mulè MP, Ruffieux H, Mescia F, Bergamaschi L, Pelly VS, Turner L, Kotagiri P; Cambridge Institute of Therapeutic Immunology and Infectious Disease–National Institute for Health Research (CITIID–NIHR) COVID BioResource Collaboration; Göttgens B, Hess C, Gleadall N, Bradley JR, Nathan JA, Lyons PA, Drakesmith H, Smith KGC. Hanson AL, et al. Nat Immunol. 2024 Mar;25(3):471-482. doi: 10.1038/s41590-024-01754-8. Epub 2024 Mar 1. Nat Immunol. 2024. PMID: 38429458 Free PMC article.
Ancient genomic linkage couples metabolism with erythroid development.
Preston AE, Frost JN, Badat M, Teh M, Armitage AE, Norfo R, Wideman SK, Hanifi M, White N, Roy N, Ghesquiere B, Babbs C, Kassouf M, Davies J, Hughes JR, Beagrie R, Higgs DR, Drakesmith H. Preston AE, et al. bioRxiv [Preprint]. 2023 Sep 25:2023.09.25.558944. doi: 10.1101/2023.09.25.558944. bioRxiv. 2023. PMID: 37808769 Free PMC article. Preprint.
Cellular iron governs the host response to malaria.
Wideman SK, Frost JN, Richter FC, Naylor C, Lopes JM, Viveiros N, Teh MR, Preston AE, White N, Yusuf S, Draper SJ, Armitage AE, Duarte TL, Drakesmith H. Wideman SK, et al. PLoS Pathog. 2023 Oct 9;19(10):e1011679. doi: 10.1371/journal.ppat.1011679. eCollection 2023 Oct. PLoS Pathog. 2023. PMID: 37812650 Free PMC article.
Another iron in C. difficile's fire.
Drakesmith H, Zimmermann MB. Drakesmith H, et al. Cell Host Microbe. 2024 Jan 10;32(1):1-2. doi: 10.1016/j.chom.2023.12.008. Cell Host Microbe. 2024. PMID: 38211560