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Page 1
Epigenetic approaches to psychiatric disorders.
Ptak C, Petronis A. Ptak C, et al. Dialogues Clin Neurosci. 2010;12(1):25-35. doi: 10.31887/DCNS.2010.12.1/cptak. Dialogues Clin Neurosci. 2010. PMID: 20373664 Free PMC article. Review.
DNA unmethylome profiling by covalent capture of CpG sites.
Kriukienė E, Labrie V, Khare T, Urbanavičiūtė G, Lapinaitė A, Koncevičius K, Li D, Wang T, Pai S, Ptak C, Gordevičius J, Wang SC, Petronis A, Klimašauskas S. Kriukienė E, et al. Nat Commun. 2013;4:2190. doi: 10.1038/ncomms3190. Nat Commun. 2013. PMID: 23877302 Free article.
DNA modification study of major depressive disorder: beyond locus-by-locus comparisons.
Oh G, Wang SC, Pal M, Chen ZF, Khare T, Tochigi M, Ng C, Yang YA, Kwan A, Kaminsky ZA, Mill J, Gunasinghe C, Tackett JL, Gottesman II, Willemsen G, de Geus EJC, Vink JM, Slagboom PE, Wray NR, Heath AC, Montgomery GW, Turecki G, Martin NG, Boomsma DI, McGuffin P, Kustra R, Petronis A. Oh G, et al. Biol Psychiatry. 2015 Feb 1;77(3):246-255. doi: 10.1016/j.biopsych.2014.06.016. Epub 2014 Jul 1. Biol Psychiatry. 2015. PMID: 25108803 Free PMC article.
A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells.
Vedadi M, Barsyte-Lovejoy D, Liu F, Rival-Gervier S, Allali-Hassani A, Labrie V, Wigle TJ, Dimaggio PA, Wasney GA, Siarheyeva A, Dong A, Tempel W, Wang SC, Chen X, Chau I, Mangano TJ, Huang XP, Simpson CD, Pattenden SG, Norris JL, Kireev DB, Tripathy A, Edwards A, Roth BL, Janzen WP, Garcia BA, Petronis A, Ellis J, Brown PJ, Frye SV, Arrowsmith CH, Jin J. Vedadi M, et al. Nat Chem Biol. 2011 Jul 10;7(8):566-74. doi: 10.1038/nchembio.599. Nat Chem Biol. 2011. PMID: 21743462 Free PMC article.
5-hmC in the brain is abundant in synaptic genes and shows differences at the exon-intron boundary.
Khare T, Pai S, Koncevicius K, Pal M, Kriukiene E, Liutkeviciute Z, Irimia M, Jia P, Ptak C, Xia M, Tice R, Tochigi M, Moréra S, Nazarians A, Belsham D, Wong AH, Blencowe BJ, Wang SC, Kapranov P, Kustra R, Labrie V, Klimasauskas S, Petronis A. Khare T, et al. Nat Struct Mol Biol. 2012 Oct;19(10):1037-43. doi: 10.1038/nsmb.2372. Epub 2012 Sep 9. Nat Struct Mol Biol. 2012. PMID: 22961382 Free PMC article.
12 results