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2012 1
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28 results

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Page 1
Amyloid Formation by Globular Proteins: The Need to Narrow the Gap Between in Vitro and in Vivo Mechanisms.
Faravelli G, Mondani V, Mangione PP, Raimondi S, Marchese L, Lavatelli F, Stoppini M, Corazza A, Canetti D, Verona G, Obici L, Taylor GW, Gillmore JD, Giorgetti S, Bellotti V. Faravelli G, et al. Front Mol Biosci. 2022 Feb 14;9:830006. doi: 10.3389/fmolb.2022.830006. eCollection 2022. Front Mol Biosci. 2022. PMID: 35237660 Free PMC article. Review.
Breakdown of supersaturation barrier links protein folding to amyloid formation.
Noji M, Samejima T, Yamaguchi K, So M, Yuzu K, Chatani E, Akazawa-Ogawa Y, Hagihara Y, Kawata Y, Ikenaka K, Mochizuki H, Kardos J, Otzen DE, Bellotti V, Buchner J, Goto Y. Noji M, et al. Commun Biol. 2021 Jan 26;4(1):120. doi: 10.1038/s42003-020-01641-6. Commun Biol. 2021. PMID: 33500517 Free PMC article.
A novel mechano-enzymatic cleavage mechanism underlies transthyretin amyloidogenesis.
Marcoux J, Mangione PP, Porcari R, Degiacomi MT, Verona G, Taylor GW, Giorgetti S, Raimondi S, Sanglier-Cianférani S, Benesch JL, Cecconi C, Naqvi MM, Gillmore JD, Hawkins PN, Stoppini M, Robinson CV, Pepys MB, Bellotti V. Marcoux J, et al. EMBO Mol Med. 2015 Oct;7(10):1337-49. doi: 10.15252/emmm.201505357. EMBO Mol Med. 2015. PMID: 26286619 Free PMC article.
Systemic Exosomal Delivery of shRNA Minicircles Prevents Parkinsonian Pathology.
Izco M, Blesa J, Schleef M, Schmeer M, Porcari R, Al-Shawi R, Ellmerich S, de Toro M, Gardiner C, Seow Y, Reinares-Sebastian A, Forcen R, Simons JP, Bellotti V, Cooper JM, Alvarez-Erviti L. Izco M, et al. Mol Ther. 2019 Dec 4;27(12):2111-2122. doi: 10.1016/j.ymthe.2019.08.010. Epub 2019 Aug 27. Mol Ther. 2019. PMID: 31501034 Free PMC article.
Proteolytic cleavage of Ser52Pro variant transthyretin triggers its amyloid fibrillogenesis.
Mangione PP, Porcari R, Gillmore JD, Pucci P, Monti M, Porcari M, Giorgetti S, Marchese L, Raimondi S, Serpell LC, Chen W, Relini A, Marcoux J, Clatworthy IR, Taylor GW, Tennent GA, Robinson CV, Hawkins PN, Stoppini M, Wood SP, Pepys MB, Bellotti V. Mangione PP, et al. Proc Natl Acad Sci U S A. 2014 Jan 28;111(4):1539-44. doi: 10.1073/pnas.1317488111. Epub 2014 Jan 13. Proc Natl Acad Sci U S A. 2014. PMID: 24474780 Free PMC article.
Class I major histocompatibility complex, the trojan horse for secretion of amyloidogenic β2-microglobulin.
Halabelian L, Ricagno S, Giorgetti S, Santambrogio C, Barbiroli A, Pellegrino S, Achour A, Grandori R, Marchese L, Raimondi S, Mangione PP, Esposito G, Al-Shawi R, Simons JP, Speck I, Stoppini M, Bolognesi M, Bellotti V. Halabelian L, et al. J Biol Chem. 2014 Feb 7;289(6):3318-27. doi: 10.1074/jbc.M113.524157. Epub 2013 Dec 13. J Biol Chem. 2014. PMID: 24338476 Free PMC article.
28 results