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Current methods to analyze lysosome morphology, positioning, motility and function.
Barral DC, Staiano L, Guimas Almeida C, Cutler DF, Eden ER, Futter CE, Galione A, Marques ARA, Medina DL, Napolitano G, Settembre C, Vieira OV, Aerts JMFG, Atakpa-Adaji P, Bruno G, Capuozzo A, De Leonibus E, Di Malta C, Escrevente C, Esposito A, Grumati P, Hall MJ, Teodoro RO, Lopes SS, Luzio JP, Monfregola J, Montefusco S, Platt FM, Polishchuck R, De Risi M, Sambri I, Soldati C, Seabra MC. Barral DC, et al. Traffic. 2022 May;23(5):238-269. doi: 10.1111/tra.12839. Epub 2022 Apr 24. Traffic. 2022. PMID: 35343629 Free PMC article. Review.
Endothelial MAPKs Direct ICAM-1 Signaling to Divergent Inflammatory Functions.
Dragoni S, Hudson N, Kenny BA, Burgoyne T, McKenzie JA, Gill Y, Blaber R, Futter CE, Adamson P, Greenwood J, Turowski P. Dragoni S, et al. J Immunol. 2017 May 15;198(10):4074-4085. doi: 10.4049/jimmunol.1600823. Epub 2017 Apr 3. J Immunol. 2017. PMID: 28373581 Free PMC article.
Cholesterol Overload: Contact Sites to the Rescue!
Enrich C, Rentero C, Grewal T, Futter CE, Eden ER. Enrich C, et al. Contact (Thousand Oaks). 2019 Jan 1;2:2515256419893507. doi: 10.1177/2515256419893507. Epub 2019 Dec 5. Contact (Thousand Oaks). 2019. PMID: 31858076 Free PMC article.
HtrA1 Mediated Intracellular Effects on Tubulin Using a Polarized RPE Disease Model.
Melo E, Oertle P, Trepp C, Meistermann H, Burgoyne T, Sborgi L, Cabrera AC, Chen CY, Hoflack JC, Kam-Thong T, Schmucki R, Badi L, Flint N, Ghiani ZE, Delobel F, Stucki C, Gromo G, Einhaus A, Hornsperger B, Golling S, Siebourg-Polster J, Gerber F, Bohrmann B, Futter C, Dunkley T, Hiller S, Schilling O, Enzmann V, Fauser S, Plodinec M, Iacone R. Melo E, et al. EBioMedicine. 2018 Jan;27:258-274. doi: 10.1016/j.ebiom.2017.12.011. Epub 2017 Dec 13. EBioMedicine. 2018. PMID: 29269042 Free PMC article.
ALIX Regulates Tumor-Mediated Immunosuppression by Controlling EGFR Activity and PD-L1 Presentation.
Monypenny J, Milewicz H, Flores-Borja F, Weitsman G, Cheung A, Chowdhury R, Burgoyne T, Arulappu A, Lawler K, Barber PR, Vicencio JM, Keppler M, Wulaningsih W, Davidson SM, Fraternali F, Woodman N, Turmaine M, Gillett C, Franz D, Quezada SA, Futter CE, Von Kriegsheim A, Kolch W, Vojnovic B, Carlton JG, Ng T. Monypenny J, et al. Cell Rep. 2018 Jul 17;24(3):630-641. doi: 10.1016/j.celrep.2018.06.066. Cell Rep. 2018. PMID: 30021161 Free PMC article.
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