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Lipid-dependent Akt-ivity: where, when, and how.
Siess KM, Leonard TA. Siess KM, et al. Biochem Soc Trans. 2019 Jun 28;47(3):897-908. doi: 10.1042/BST20190013. Epub 2019 May 30. Biochem Soc Trans. 2019. PMID: 31147387 Free PMC article. Review.
Structure of autoinhibited Akt1 reveals mechanism of PIP3-mediated activation.
Truebestein L, Hornegger H, Anrather D, Hartl M, Fleming KD, Stariha JTB, Pardon E, Steyaert J, Burke JE, Leonard TA. Truebestein L, et al. Proc Natl Acad Sci U S A. 2021 Aug 17;118(33):e2101496118. doi: 10.1073/pnas.2101496118. Proc Natl Acad Sci U S A. 2021. PMID: 34385319 Free PMC article.
Structures of three MORN repeat proteins and a re-evaluation of the proposed lipid-binding properties of MORN repeats.
Sajko S, Grishkovskaya I, Kostan J, Graewert M, Setiawan K, Trübestein L, Niedermüller K, Gehin C, Sponga A, Puchinger M, Gavin AC, Leonard TA, Svergun DI, Smith TK, Morriswood B, Djinovic-Carugo K. Sajko S, et al. PLoS One. 2020 Dec 9;15(12):e0242677. doi: 10.1371/journal.pone.0242677. eCollection 2020. PLoS One. 2020. PMID: 33296386 Free PMC article.