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Pure MnTBAP selectively scavenges peroxynitrite over superoxide: comparison of pure and commercial MnTBAP samples to MnTE-2-PyP in two models of oxidative stress injury, an SOD-specific Escherichia coli model and carrageenan-induced pleurisy.
Batinić-Haberle I, Cuzzocrea S, Rebouças JS, Ferrer-Sueta G, Mazzon E, Di Paola R, Radi R, Spasojević I, Benov L, Salvemini D. Batinić-Haberle I, et al. Free Radic Biol Med. 2009 Jan 15;46(2):192-201. doi: 10.1016/j.freeradbiomed.2008.09.042. Epub 2008 Nov 1. Free Radic Biol Med. 2009. PMID: 19007878 Free PMC article.
Lipophilicity is a critical parameter that dominates the efficacy of metalloporphyrins in blocking the development of morphine antinociceptive tolerance through peroxynitrite-mediated pathways.
Batinić-Haberle I, Ndengele MM, Cuzzocrea S, Rebouças JS, Spasojević I, Salvemini D. Batinić-Haberle I, et al. Free Radic Biol Med. 2009 Jan 15;46(2):212-9. doi: 10.1016/j.freeradbiomed.2008.09.037. Epub 2008 Oct 17. Free Radic Biol Med. 2009. PMID: 18983908 Free PMC article.