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15-lipoxygenase 2 (15-LOX2) is a functional tumor suppressor that regulates human prostate epithelial cell differentiation, senescence, and growth (size).
Prostaglandins Other Lipid Mediat. 2007 Jan;82(1-4):135-46. doi: 10.1016/j.prostaglandins.2006.05.022. Epub 2006 Jul 7.
Prostaglandins Other Lipid Mediat. 2007.
PMID: 17164141
Review.
Cell-autonomous induction of functional tumor suppressor 15-lipoxygenase 2 (15-LOX2) contributes to replicative senescence of human prostate progenitor cells.
Bhatia B, Tang S, Yang P, Doll A, Aumüeller G, Newman RA, Tang DG.
Bhatia B, et al.
Oncogene. 2005 May 19;24(22):3583-95. doi: 10.1038/sj.onc.1208406.
Oncogene. 2005.
PMID: 15750631
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