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Synergism between remdesivir and ribavirin leads to SARS-CoV-2 extinction in cell culture.
García-Crespo C, de Ávila AI, Gallego I, Soria ME, Durán-Pastor A, Somovilla P, Martínez-González B, Muñoz-Flores J, Mínguez P, Salar-Vidal L, Esteban-Muñoz M, Cañar-Camacho E, Ferrer-Orta C, Zuñiga S, Sola I, Enjuanes L, Esteban J, Fernández-Roblas R, Gadea I, Gómez J, Verdaguer N, Domingo E, Perales C. García-Crespo C, et al. Br J Pharmacol. 2024 Aug;181(15):2636-2654. doi: 10.1111/bph.16344. Epub 2024 Apr 14. Br J Pharmacol. 2024. PMID: 38616133
Incipient functional SARS-CoV-2 diversification identified through neural network haplotype maps.
Delgado S, Somovilla P, Ferrer-Orta C, Martínez-González B, Vázquez-Monteagudo S, Muñoz-Flores J, Soria ME, García-Crespo C, de Ávila AI, Durán-Pastor A, Gadea I, López-Galíndez C, Moran F, Lorenzo-Redondo R, Verdaguer N, Perales C, Domingo E. Delgado S, et al. Proc Natl Acad Sci U S A. 2024 Mar 5;121(10):e2317851121. doi: 10.1073/pnas.2317851121. Epub 2024 Feb 28. Proc Natl Acad Sci U S A. 2024. PMID: 38416684 Free PMC article.