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Pharmacological inhibition of the integrated stress response accelerates disease progression in an amyotrophic lateral sclerosis mouse model.
Br J Pharmacol. 2024 Feb;181(3):495-508. doi: 10.1111/bph.16260. Epub 2023 Dec 7.
Br J Pharmacol. 2024.
PMID: 37823684
GCN2 inhibition reduces mutant SOD1 clustering and toxicity and delays disease progression in an amyotrophic lateral sclerosis mouse model.
Ortiz DA, Peregrín N, Valencia M, Vinueza-Gavilanes R, Marín-Ordovas E, Ferrero R, Nicolás MJ, González-Aseguinolaza G, Arrasate M, Aragón T.
Ortiz DA, et al.
Transl Neurodegener. 2024 Sep 20;13(1):49. doi: 10.1186/s40035-024-00441-w.
Transl Neurodegener. 2024.
PMID: 39304897
Free PMC article.
No abstract available.
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